Arthritis is positively associated with the decline of sex hormones, especially estrogen. Tamoxifen (TMX) is a selective estrogen receptor modulator, possessing agonist or antagonistic activity in dif
To obtain AIA-related genes [the significant differentially expressed genes (DEGs) of AIA model group vs. Normal control group], the microarray analysis was carried out. Overall design: 6 rat samples
Untargeted metabolomics with ultrahigh performance liquid chromatography-tandem mass spectroscopy (UPLC-MS/MS) was done on plasma of collagen-induced arthritis (CIA) mouse model. Data keys and explana
Additional file 10: Table S2. Podocyte-specific sequencing data – statistical analyses. Differential expression between male & female vehicle groups. Differential expression between male & fem
A toxicogenomic approach was used to assess the sex-specific transcriptomic changes in kidney tissue of rats from a one generation reproductive toxicity study. Transcriptomic data from both F0 and F1,