Expression data from coculture of retinoblastoma (RB) and bone marrow stromal cells (BMSC). Expression data from coculture of retinoblastoma (RB) and bone marrow stromal cells (BMSC)

The study hypothesizes that tumor microenvironment is responsible for progression of RB tumors. We performed whole genome microarray on direct cocultures of RB cells and BMSC. RB cells (NCC-RbC-51 and Weri-Rb-1) were cocultured with BMSC for 24 hrs. Total RNA was isolated and whole genome microarray was performed. Overall design: Whole genome microarrays were used to analyze the pattern of differentially expressed genes in coculture samples of RB and BMSC cells.