Transporters of the BBB.

A) BBB enriched transporters. Transporters from the Slc, Slco, ATP and Abc gene families with enriched expression in brain endothelial cells. Transporters identified in Table S6, all of which have at least a two-fold greater expression value in brain GFP+ than liver and lung GFP+ cells, pericyte genes excluded.
B) Endothelial transporters. Transporters expressed in multiple endothelial samples. These transporters were identified as endothelial specific in Table S2, but were not significantly enriched in brain GFP+ cells compared to either the liver GFP+ or lung GFP+ samples.
C) Pericyte enriched transporters. A list of pericyte enriched transporters from Table S3, defined as those transcripts whose GeneChip expression values have a brain vascular:endothelial ratio of ≥2.