A hypothetical example demonstrating the effect of heterogeneity (cases without the minor allele affecting disease) in data with 1000 cases (MAF 30.0%) and 1000 controls (MAF 38.0%).
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https://figshare.com/articles/dataset/_A_hypothetical_example_demonstrating_the_effect_of_heterogeneity_cases_without_the_minor_allele_affecting_disease_in_data_with_1000_cases_MAF_30_0_and_1000_controls_MAF_38_0_/777627
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The p-value, at the border of genome-wide significance, lowers as the percentage of heterogeneity (with MAF as given by cases) increases.
创建时间：
2015-12-02
