A hypothetical example demonstrating the effect of heterogeneity (cases without the minor allele affecting disease) in data with 1000 cases (MAF 30.0%) and 1000 controls (MAF 38.0%).
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The p-value, at the border of genome-wide significance, lowers as the percentage of heterogeneity (with MAF as given by cases) increases.
创建时间:
2015-12-02



