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Gene expression profiles of MLL-AF9 leukemia cells treated with FF-10501-01

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https://www.ncbi.nlm.nih.gov/sra/SRP400298
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To assess the molecular changes induced by IMPDH inhibition in MLL-AF9 leukemia, we examined gene expression profiles of vehicle- or FF-10501-01-treated MLL-AF9 cells by RNA-seq. Overall design: FF-10501-01 was orally administered to leukemic mice for two consecutive days. 48 hours after first treatment, GFP+ leukemia cells were collected from bone marrow and isolated using cell sorter before RNA extraction.
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2023-01-01
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