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β-D-N(4)-hydroxycytidine is a potent anti-alphavirus compound that induces high level of mutations in viral genome

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NIAID Data Ecosystem2026-03-11 收录
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The goal of this project was the analysis of virus variants resistant to β-D-N(4)-hydroxycytidine. Venezuelan equine encephalitis virus TC-83 was passaged on Vero cells for 20 passages in the presence or absence of β-D-N(4)-hydroxycytidine. Virus samples were collected at passages 0, 5 10, 15 and 20. Total virion RNAs were isolated and sequenced.

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2019-07-09
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