Gene ontology (GO) enrichment analysis results for significantly upregulated genes at all time points.

The analysis was performed using the topGO R Bioconductor package. The statistical metrics presented for each process include: the total number of genes annotated to the process (Total annotated), the number of genes that were significantly up (N up) -regulated, the percent of total annotated that were up-regulated (% Up) and the number that were expected by chance (Expected). The uncorrected Fisher’s exact test p-value (Pvalue) and overall rank for over-representation of the GO term in the set using both the classic and weight01 (W1) algorithms are presented. (XLSX)