Cryo-EM structure of the TUG-891 bound FFA4-Gq complex

Cryo-EM structure of the TUG-891 bound FFA4-Gq complex Descriptor: (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, ... Authors: Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. Deposit date: 2023-06-07 Release date: 2024-01-17 Last modified: 2025-05-14 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Structural basis for the ligand recognition and signaling of free fatty acid receptors. Sci Adv, 10, 2024