首页/数据集/Genome-wide analysis identifies aberrant methylation in Fragile X syndrome is specific to the FMR1 locus

Genome-wide analysis identifies aberrant methylation in Fragile X syndrome is specific to the FMR1 locus

ChEBI2013-04-15 更新2026-07-21 收录

脆性X染色体综合征

FMR1基因甲基化

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-41273 数据链接链接失效反馈

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Genome-wide analysis identifies aberrant methylation in Fragile X syndrome is specific to the FMR1 locus

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创建时间：

2013-04-15

DNA甲基化分析

脆性X染色体综合征

Additional file 8: Table S5. List of DMRs and their chromosome position in the comparison between WT1 and WT2 versus FXS2.

NIAID Data Ecosystem80

Supplementary material_genotype ALSPAC FRAXA/E data.docx

脆性X染色体综合征

基因重复分析

Supplementary data of number of repeats at FRAXA/FRAXE from the ALSPAC study. This data is supplementary to the paper Clark, R., Gregory, S., Ring, S., Jacobs, P., Ennis, S., Murray, A., ... & Pem

Figshare2020-01-23 更新10

Spatially coordinated heterochromatinization of long synaptic genes in fragile X syndrome [CUT&RUN]. Spatially coordinated heterochromatinization of long synaptic genes in fragile X syndrome [CUT&RUN]

脆性X染色体综合征

染色体构象与基因沉默

Short tandem repeat (STR) instability causes transcriptional silencing in several repeat expansion disorders. In fragile X syndrome (FXS), mutation-length expansion of a CGG STR represses FMR1 via loc

NIAID Data Ecosystem10

FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism (H3K36me3 ChIP-seq)

脆性X染色体综合征

自闭症基因

Silencing of FMR1 and loss of its gene product FMRP results in Fragile X Syndrome. FMRP binds brain mRNAs and inhibits polypeptide elongation. Using ribosome profiling of the hippocampus, we find that

NIAID Data Ecosystem30

Volume of interest-based correlation between FMZ BP and IQ and index scores for the healthy volunteers and fragile X patients.

神经学评估

脆性X染色体综合征

Abbreviations: TIQ: total IQ score, VIQ: verbal IQ, PIQ: performance IQ, VCI: verbal comprehension index, POI: perceptual organization index, WMI: working memory index, PSI: processing speed index.

NIAID Data Ecosystem10

Genome-wide analysis identifies aberrant methylation in Fragile X syndrome is specific to the FMR1 locus

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