Additional file 11 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients

Additional file 11: Supplementary Table 7. Genes differentially expressed in female and male, 15–18-month-old, 3xTg-AD mice compared to controls. Total RNA was isolated from the bulk brain tissue of 15–18- month-old, female and male, 3xTg-AD and WT mice, and sequenced. Differential expression analyses were performed between female 3xTg-AD and WT mice (n = 6 3xTg-AD, 6 WT) as well as between male 3xTg-AD and WT mice (n = 6 3xTg-AD, 6 WT) with a negative binomial generalized linear model.