Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells
收藏干细胞与再生医学数据中心2021-09-08 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=1665b75ee9b5494682a744a56abce207
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资源简介：
To detect the modification site of m6A and the binding gene of Ythdf1 in dendritic cells, MeRIP-seq and RIP-seq were used to obtain the binding gene set. In order to compare the effect of Ythdf1 knockout on gene translation efficiency in dendritic cells, Ribo-seq was performed on the cells with Ythdf1 knockout and control. Based on MeRIP-seq and RIP-seq data, we analyzed the genes regulated by m6a-Ythdf1, which can affect the efficiency of RNA translation. And those genes and signaling pathways are mainly regulated by Ythdf1 in dendritic cells.
提供机构：
中国科学院北京基因组研究所
创建时间：
2021-09-08
