Characteristics of the 3 cell line clusters in terms of DNA repair sub-pathway response to the drugs treatments (see Fig. 3).

Text in bold indicates the repair activities significantly inhibited.
Text in italics indicates the repair activities significantly stimulated.
For the two clusters composed of three cell lines, the Wilcoxon test was used to investigate if repair toward the different lesions was either stimulated or inhibited. Results with P value<0.05 (noted **) or <0.1 (noted *) are reported. For RPMI-8226 cluster, as only two data by treatment and lesion type were available, repair was considered either stimulated (positive value) or inhibited (negative value) when |mean|>3×standard error. For each cluster and treatment, lesions exhibiting significant repair inhibition after treatment were displayed in bold, and lesions exhibiting significant repair stimulation after treatment were displayed in italics.