*The numbers in the right two columns are M value. A value of 1.0 corresponds to a 2-fold increase in expression compared to the wild type and a −1.0 means a 2-fold decrease compared to the wild type.
The goal of this experiment is to identify genes differentially expressed in MEF cell lines with a targeted MDMX mutation that prevents binding and inhibition of CK1-alpha kinase. Overall design: MDMX
Differential gene expression with the number of up-regulated and down-regulated probes (False discovery rate (FDR) of 0.05, NS = not significant), as a consequence of full trisomy (pairwise comparison