Spermatogenesis following male germ-cell transplantation.
收藏PubMed Central1994-11-22 更新2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC45218/
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资源简介:
In the adult male, a population of diploid stem-cell spermatogonia continuously undergoes self-renewal and produces progeny cells, which initiate the complex process of cellular differentiation that results in mature spermatozoa. We report here that stem cells isolated from testes of donor male mice will repopulate sterile testes when injected into seminiferous tubules. Donor cell spermatogenesis in recipient testes showed normal morpholigical characteristics and produced mature spermatozoa. This methodology, besides opening new avenues of basic research into spermatogenesis and stem-cell self-renewal, may prove useful as a tool for biomedical science and biotechnology. IMAGES:
提供机构:
National Academy of Sciences
创建时间:
1994-11-22



