Plasmodium vivax in the Democratic Republic of the Congo

We investigated the recent finding that Plasmodium vivax transmission is occurring among Duffy-negative hosts in sub-Saharan Africa. Using isolates from the 2013-2014 Democratic Republic of the Congo Demographic Health Survey, we screened approximately 17,000 adults for P. vivax. We found a nearly 3% prevalence across the DRC. Nearly all infections were among Duffy-negative adults. We then used a mix of epidemiologic, spatial, and genomic approaches to identify who was infected, where infectious were occurring, and the likely origin of these infections. These are the three genomes that we generated with hybrid capture.