Hepatocyte_Toxicology_Data_Supplement_081219

Dryad2019-01-01 更新2026-04-13 收录

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资源简介：

Supplemental Information file containing figures and methods relevant to the manuscript, but not included in the main text.

创建时间：

2019-01-01

Viability assay of the cells in vivo conditions after exposure to tested triterpenes 1–6.

细胞毒性评估

三萜化合物药效学

Viability assay of the cells in vivo conditions after exposure to tested triterpenes 1–6.

Figshare2019-03-28 更新20

The IC 50 of tylophora alkaloids analogs on the growth inhibition of HepG2 and Huh 7 cells.

药物筛选

细胞毒性评估

The IC50 of these compounds are significantly different (p<0.05) from each other in different magnitude (nM vs µM); while compounds with the same magnitude (nM vs nM and µM vs µM) are not significantl

NIAID Data Ecosystem10

Cytotoxicity of Naps on THP-1 cells.

细胞毒性评估

体外生物安全性测试

Results of LDH release (measured by the OD490 of assays on cell supernatants) from THP-1 cells in the presence of individual mNaps. Lysis buffer shows the LDH release from 100% of cells. (XLSX)

NIAID Data Ecosystem00

Comparison of Cellular Morphological Descriptors and Molecular Fingerprints for the Prediction of Cytotoxicity- and Proliferation-Related Assays

细胞毒性评估

细胞增殖预测

Cell morphology features, such as those from the Cell Painting assay, can be generated at relatively low costs and represent versatile biological descriptors of a system and thereby compound response.

Figshare2021-02-01 更新20

Cytotoxicity evaluation by MTT assay (IC 50 , mM) of compounds 1a, 1d, 1h, 2d, 2f, and acetohydroxamic acid a .

毒性筛查

细胞毒性评估

Cytotoxicity evaluation by MTT assay (IC50, mM) of compounds 1a, 1d, 1h, 2d, 2f, and acetohydroxamic acida.

NIAID Data Ecosystem00