Targeting PGC-1a in Bladder Cancer: Unraveling Energy Metabolism Reprogramming for Therapeutic Intervention

This study aims to explore the effect of PGC-1 a siRNA delivered by liposomal nanoparticles on cancer cells through transcriptome, proteome and metabolome technologies, so as to reveal its regulatory effect on cancer cell reprogramming and energy metabolism, so as to provide clues for the molecular mechanism of the treatment of metastatic bladder cancer