Structure of Cysteine-free Human Insulin-Degrading Enzyme in complex with Substrate-selective Macrocycle Inhibitor 63
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Structure of Cysteine-free Human Insulin-Degrading Enzyme in complex with Substrate-selective Macrocycle Inhibitor 63 Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Insulin-degrading enzyme, {(8R,9S,10S)-9-(2',3'-dimethyl[1,1'-biphenyl]-4-yl)-6-[(1-methyl-1H-imidazol-2-yl)sulfonyl]-1,6-diazabicyclo[6.2.0]decan-10-yl}methanol Authors: Tan, G.A, Seeliger, M.A, Welsh, A.J, Maianti, J.P, Liu, D.R. Deposit date: 2018-10-09 Release date: 2019-04-03 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.56914708689 Å) Cite: Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme. Nat.Chem.Biol., 15, 2019
创建时间：
2018-10-09
