C. elegans embryogenesis

scRNA-seq time-series dataset of C. elegans embryogenesis assayed using 10x genomics v2 chemistry. Packer et al. (Science 2019) assigned cells to the known C. elegans lineage tree based on marker gene expression and assigned a time label to each cell by comparing it with a bulk reference time course. Following Forrow et al. (Nat. Comms 2021), this dataset represents a subset of the original data, containing all 46,151 cells with at least partial lineage information. This dataset contains raw counts. <br> Please cite the original publication: https://doi.org/10.1126/science.aax1971

搜集汇总

背景与挑战

背景概述

该数据集是一个秀丽隐杆线虫胚胎发育的单细胞RNA测序时间序列数据集，包含46,151个具有至少部分谱系信息的细胞和原始计数，用于研究胚胎发育过程中的基因表达和谱系追踪。数据基于10x genomics v2化学方法生成，并已通过标记基因表达分配了谱系和时间标签，适用于生物信息学方法和发育生物学研究。