Crystal structure of renin in complex with NVP-BGQ311 (compound 12)
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Crystal structure of renin in complex with NVP-BGQ311 (compound 12) Descriptor: (3S,5R)-N-{[9-(4-methoxybutyl)-9H-xanthen-9-yl]methyl}-5-{[(4-methylphenyl)sulfonyl]amino}piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, ... Authors: Ostermann, N, Zink, F, Kroemer, M. Deposit date: 2012-08-09 Release date: 2013-02-13 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.65 Å) Cite: A novel class of oral direct Renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore. J.Med.Chem., 56, 2013
创建时间：
2012-08-09
