Tandem Radical Fluoroalkylation–Cyclization: Synthesis of Tetrafluoro Imidazopyridines
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https://figshare.com/articles/dataset/Tandem_Radical_Fluoroalkylation_Cyclization_Synthesis_of_Tetrafluoro_Imidazopyridines/2080768
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资源简介:
A copper-catalyzed
fluoroalkylation–cyclization sequence
of alkenes and alkynes enables the synthesis of fluorinated tetra-
and dihydroimidazopyridines in moderate to excellent yields
within 1 h at 70 °C. This reaction, which is carried out using
copper(I) acetate as the catalyst, makes use of a new class of functionalized
tetrafluoroethyl reagents based on a hypervalent iodine scaffold.
创建时间:
2016-02-12



