Summary of the factorial experiment.

The first column lists the phenotypes studied. Columns 2–5 list the main effects of 4 factors- genotype, strain, diet, and sex. Columns 6–11 list the interactions between genotype, strain, diet, and sex. ‘Y’ indicates that a main effect or interaction influences the phenotype. ‘−’ indicates no main effect. ‘+’ indicates that the factor had no main effect, but influences the phenotype when interacting with one or more of the other factors. ‘NA’ indicates that the factor was not included or assessed in the experiment. ∧As more data were available for F1 and B6 mice on cholate, than control, diet, only results of analysis of cholate diet are shown here. #For percent liver weight relative to final body weight, a 3-way interaction was detected between strain, diet, and genotype.