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Childhood Cancer Data Initiative (CCDI): Clonal Evolution During Metastatic Spread in High-Risk Neuroblastoma

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NIAID Data Ecosystem2026-04-30 收录
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https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs003111.v1.p1
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The goal of this study is to deliver a detailed characterization of the patterns of disease dissemination at diagnosis, during progression and in response to therapy in high-risk neuroblastoma. Longitudinal and spatially distinct tumors were collected from patients. Clinical data includes diagnosis and treatment information. Biospecimen data includes whole genome sequencing (WGS) and whole transcriptome sequencing (WTS).]]> All neuroblastoma patients treated at MSKCC with two or more tumors from distinct sites or time points were eligible for this study. No exclusion criteria.]]> Samples available through 1987 through 2021 were analyzed.]]>
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2022-11-09
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