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Vaccine-Elicited CD4 T Cells Induce Immunopathology Following Chronic LCMV Infection

ChEBI2014-12-04 更新2026-07-21 收录

疫苗免疫病理

慢性病毒感染免疫

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-63825 数据链接链接失效反馈

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Vaccine-Elicited CD4 T Cells Induce Immunopathology Following Chronic LCMV Infection

应用场景：

创建时间：

2014-12-04

慢性病毒感染免疫

单细胞T细胞图谱

Dataset of virus-specific (P14) CD8T cells in chronic LCMV infection across multiple tissues (blood, spleen, bone marrow, lymphnode, lung, liver), transcriptome sequenced by 10x at single-cell resolut

Figshare2024-07-24 更新60

Role of GITR on CD4 T cells in control of chronic LCMV clone 13 infection in mice

慢性病毒感染免疫

细胞基因调控

genes induced by stimulatory molecule GITR in mouse CD4 T cells during chronic infection

NIAID Data Ecosystem60

Life-long control of cytomegalovirus (CMV) by T resident memory cells in the adipose tissue results in inflammation and hyperglycemia

慢性病毒感染免疫

代谢综合征

Cytomegalovirus (CMV) is a ubiquitous herpesvirus infecting most of the world’s population. CMV has been rigorously investigated for its impact on lifelong immunity and potential complications arising

NIAID Data Ecosystem50

Pd-1 High and Intermediate CD8+ T cells

T细胞耗竭

慢性病毒感染免疫

During acute viral infections, naïve CD8+ T cells differentiate into effector CD8+ T cells and, after viral control, into memory CD8+ T cells. Memory CD8+ T cells are highly functional, proliferate ra

NIAID Data Ecosystem60

RNA-seq of Tfh IL21+ single producers and Tfh IL21+ IL10+ double producers

T细胞转录组学

慢性病毒感染免疫

During chronic viral infection, the inflammatory function of CD4 T cells becomes gradually attenuated. Concurrently, Th1 cells progressively acquire the capacity to secrete the cytokine IL-10, a poten

NIAID Data Ecosystem50

Vaccine-Elicited CD4 T Cells Induce Immunopathology Following Chronic LCMV Infection

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