One-Pot Approach to N‑Quinolyl 3′/4′-Biaryl Carboxamides by Microwave-Assisted Suzuki–Miyaura Coupling and N‑Boc Deprotection

N-Quinolyl biaryl carboxamides have received tremendous attention for their notable biological properties. Here we have described a general protocol for the preparation of N-quinolyl 3′/4′-biaryl carboxamides by microwave-assisted Suzuki–Miyaura cross-coupling reaction and N-Boc deprotection in one pot. This method, which did not require acids, was used to produce a series of N-quinolyl 3′/4′-biaryl carboxamides with excellent functional group tolerance and high yields (70% to 95%).