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Promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging

ChEBI2011-03-17 更新2026-07-21 收录

表观遗传调控

造血细胞分化

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-487 数据链接链接失效反馈

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Promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging

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创建时间：

2011-03-17

肝病相关单核细胞功能障碍

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BACKGROUND/ AIMS: Severe forms of alcoholic liver disease are associated with increased susceptibility to infections largely due to immune dysfunction. In this study, we analyze the phenotypic, molecu

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Skeletal muscle is a metabolically active organ, but it remains largely unexplored in obesity. Here, we used diet-induced mice as obesity model to investigate the effect of obesity on muscle transcrip

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ARID1B regulates BCL11B-mediated non-canonical Activin signaling to maintain mesenchymal stem cell homeostasis in the mouse incisor [scRNA-seq]

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ARID1B is a epigenetic regulator. We used the scRNA sequencing to analysis the role of ARID1B in regulating mouse incisor tissue homeostasis. Single-cell transcriptomes were obtained from the digested

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mRNA profiling of Pontin WT and RA under glucose starvation

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To determine which genes are affected by methylated Pontin, we performed RNA-sequencing (RNA-seq) in Pontin WT and RA MEFs after glucose starvation. Overall design: mRNA expression profiles of Pontin

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DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]

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DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

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Promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging

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