Additional file 6: Table S5. The methylation loci and corresponding genes involved in MAPK signalling, pyruvate metabolism, glycolysis, and proteoglycan pathways.
c-Myc (hereafter called Myc) belongs to a family of transcription factors that regulates cell growth, cell proliferation, and differentiation. Myc initiates the transcription of a large cast of genes
Altered metabolism is an important part of malignant transformation of tumor cells. Oncogenic transformation may reprogram tumor metabolism and render tumor cells addicted to extracellular nutrients.
In vitro and in vivo growth screen data, HCC827 cells, Source data for Fig 1. Mini-library CRISPRi screen in HCC827 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank a
