Gene expression profile at single cell level of CD45+ immune cells from E0771-Vector control tumor tissue, E0771 wildtype Malt1 overexpression tumor tissue and E0771 paracaspase-deficient Malt1 overexpression tumor tissue.
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https://www.ncbi.nlm.nih.gov/sra/SRP459098
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To invesitigate the additional paracaspase-independent tumor-promoting effect exist for Malt1. We thus collected E0771-Vector control tumor tissue, E0771 wildtype Malt1 (Malt1-WT) overexpression tumor tissue and E0771 paracaspase-deficient Malt1 (Malt1-PD) overexpression tumor tissue, and sorted out immune cells for 10Ã Genomics single cell RNA-sequencing (scRNA-seq). Overall design: First inject E0771-Vector control,E0771 Malt1-WT overexpression, and E0771 Malt1-PD overexpression cells into the mammary fatty pad of C57B6/J mice to form tumor. We thus collected E0771-Vector control tumor tissue, E0771 Malt1-WT overexpression tumor tissue and E0771 paracaspase-deficient Malt1 (Malt1-PD) overexpression tumor tissue, and sorted out immune cells by FACS for 10Ã Genomics single cell RNA-sequencing (scRNA-seq).
创建时间:
2024-04-19



