PRMT6 and PARP1 sequencing in non-treated MDA-MB-231 cells. PRMT6 and PARP1 sequencing in non-treated MDA-MB-231 cells

Here, we examined the interactions between PRMT6, poly(ADP-ribose) polymerase 1 (PARP1), and the cullin 4 B (CUL4B)-Ring E3 ligase (CRL4B) complex, to form a transcription-repressive complex that co-occupies the core clock gene PER3 promoter. Overall design: Examination of PRMT6 and PARP1 target genes in MDA-MB-231 cell line.