poly(A)+ RNA-seq of HepG2 cells upon CRISPRa-mediated Hep-ncR1/LINC01093 lncRNA upregulation

NIAID Data Ecosystem2026-03-13 收录

癌症分子机制

非编码RNA功能

数据链接：

https://www.ncbi.nlm.nih.gov/sra/DRP008264 数据链接链接失效反馈

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资源简介：

To search target genes of Hep-ncR1/LINC01093 lncRNA in HepG2 cells and investigate roles of the lncRNA in hepatocarcinoma.

创建时间：

2022-03-07

Chromatin accessbility profile (ATAC-Seq) in mouse colonic epithelium and tumor expressing endogenouse K-Ras-WT or oncogenic K-Ras-G12D

癌症分子机制

表观遗传调控

K-Ras is frequently hyperactivated in human cancers through gain-of-function mutations that drive tumorigenesis. K-RasG12D, the most common oncogenic K-Ras allele, triggers massive transcriptomic and

NIAID Data Ecosystem40

Additional file 3 of ALKBH5 prevents hepatocellular carcinoma progression by post-transcriptional inhibition of PAQR4 in an m6A dependent manner

癌症分子机制

依赖性基因调控

Additional file 3. Overexpression of ALKBH5 decreased the proliferation capacity in 2 HCC cell lines, while co-overexpressed of PAQR4 reverted this phenomenon (A and B). Overexpression of ALKBH5 decre

NIAID Data Ecosystem30

PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance [ChIP-seq batch2]

癌症分子机制

转录因子功能基因组学

Aberrant activation of embryonic signaling pathways is frequent in pancreatic ductal adenocarcinoma (PDA) making developmental regulators therapeutically attractive. Here, we demonstrate diverse funct

NIAID Data Ecosystem00

miRNA expression signatures in multiple myeloma. miRNA expression signatures in multiple myeloma

多发性骨髓瘤miRNA表达

癌症分子机制

In the present study, miRNome profiling was carried out to investigate the microRNA expression patterns of multiple myeloma patients and to assess the pathogenetic role of differentially expressed miR

NIAID Data Ecosystem40

DataSheet4_PRR11 promotes cell proliferation by regulating PTTG1 through interacting with E2F1 transcription factor in pan-cancer.zip

癌症分子机制

细胞周期调控

The upregulated proline rich 11 (PRR11) plays a critical role in cancer progression. The relevant biological functions of PRR11 in pan-cancer development are not well understood. In the current study,

NIAID Data Ecosystem30

poly(A)+ RNA-seq of HepG2 cells upon CRISPRa-mediated Hep-ncR1/LINC01093 lncRNA upregulation

资源简介：

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