Oxidative stress correlates with more aggressive features in thyroid cancer.

This dataset contains the RAW data for the paper "Oxidative stress correlates with more aggressive features in thyroid cancer". In this paper, we investigated the thyroid differentiation score-TDS in malignant and benign thyroid lesions and normal tissues. A custom AmpliSeq RNA expression panel (Illumina) was designed by the GenomeStudio software to detect the expression of 16 thyroid function genes (DIO1, DIO2, DUOX1, DUOX2, FOXE1, GLIS3, NKX21, PAX8, SLC26A4, SLC5A5, SLC5A8, TG, THRA, THRB, TSHR and TPO) and of the housekeeping gene TBP. The mRNA expression level of the 16 thyroid function genes was used to derive the Thyroid Differentiation Score (TDS).