Model design choices impact biological insight: Unpacking the broad landscape of spatial-temporal model development decisions: NUTRIENT DYNAMICS

Data and results for NUTRIENT DYNAMICS simulations.

Simulations of cancerous cells in colony and tissue contexts with different nutrient levels of blood glucose and temporal nutrient concentration dynamics. Each condition is run for 15 days (21600 ticks) with 50 replicates (random seeds 0 - 49). Cancerous cells (max_height x 1.5, meta_pref x 1.5, migra_threshold x 0.5) are introduced to the center of the environment after a 1 day delay. Snapshots are taken every 0.125 days (180 ticks).

The data folder contains .tar.xz compressed replicate sets. The results folder contains .csv.xz files of compressed parsed data.

Simulations are labelled as: [context]_[level]_[profile]

- [context]
- C = colony context, cancerous cells only
- CH = tissue context, cancerous cells and healthy cells
- [level]
- BASAL = basal blood glucose concentration
- LOW = low blood glucose concentration (half basal value)
- HIGH = high blood glucose concentration (double basal value)
- [profile]
- constant = constant glucose levels
- pulse = pulses of glucose every two days
- cycle = cyclic glucose with three peaks a day

本数据集包含了营养动态模拟的数据与结果。该数据集模拟了在不同血糖水平和时间营养浓度动态下的癌细胞在群体和组织环境中的生长情况。每个条件模拟运行15天（21600个时间单位），进行50次重复实验（随机种子0-49）。在延迟1天后，将癌细胞（最大高度为max_height x 1.5，元偏好为meta_pref x 1.5，迁移阈值migra_threshold x 0.5）引入环境中心。每隔0.125天（180个时间单位）进行一次快照。数据文件夹包含.tar.xz压缩的重复实验集。结果文件夹包含.csv.xz压缩解析数据文件。模拟标签为：[环境]_[水平]_[模式]。

- [环境]
- C = 群体环境，仅包含癌细胞
- CH = 组织环境，包含癌细胞和健康细胞
- [水平]
- BASAL = 基础血糖浓度
- LOW = 低血糖浓度（基础值的一半）
- HIGH = 高血糖浓度（基础值的两倍）
- [模式]
- constant = 恒定血糖水平
- pulse = 每两天一次的葡萄糖脉冲
- cycle = 每天三个波峰的循环葡萄糖。