​​A randomized multicenter non-inferiority phase III trial of chemoradiotherapy and local excision versus total mesorectal excision in T2–T3ab,N0,M0 rectal cancer (the TAUTEM study)​

​​According to international guidelines, the standard treatment of stage T2-T3ab,N0,M0 rectal cancer is total mesorectal excision (TME). The TAUTEM study is a multicenter phase III trial designed to assess an alternative treatment that preserves the rectum applying oncological non-inferiority criteria​