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Depletion of PfAP2-MRP increases chromatin accessibility

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA847684
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资源简介:
The Plasmodium falciparum PfAP2-MRP protein is one of 8 ApiAP2 proteins that strongly associate with the parasite's heterochromatin regions. PfAP2-MRP associates with many heterochromatin associated genes that serve a role in antigenic variation. We explored the effects of pfap2-mrp deletion on chromatin structure by whole-genome chromosome conformation capture (Hi-C) followed by deep sequencing of tagged and knockout strains at 16 and 40 h.p.i..
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2022-06-09
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