Over-expression of the polycomb group gene BMI-1 is implicated in the pathogenesis of many human cancers. In this study, we investigate the role of BMI-1 as a functional oncogene in the Ewing’s Sarcom

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Genome-wide chromatin analysis of Ewing sarcoma (ChIP-seq). Genome-wide chromatin analysis of Ewing sarcoma (ChIP-seq)

尤文肉瘤

ChIP-seq

As the second most common malignant bone tumor in children and adolescents, Ewing sarcoma is initiated and exacerbated by a chimeric oncoprotein, most commonly, EWS-FLI1. In this study, we apply epige

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Overexpression of HOX genes is prevalent in Ewing sarcoma and is associated with altered epigenetic regulation of developmental transcription programs

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表观遗传调控

The polycomb proteins BMI-1 and EZH2 are highly overexpressed by Ewing sarcoma (ES), a tumor of stem cell origin that is driven by EWS-ETS fusion oncogenes, most commonly EWS-FLI1. In the current stud

DataCite Commons2020-09-04 更新60

Additional file 4 of CRISPR-Cas9 knockout screening identifies KIAA1429 as an essential gene in Ewing sarcoma

CRISPR-Cas9

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Additional file 4.

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