Genomic Signatures Reveal DNA Damage Response Deficiency in Brain Metastases of Colorectal Cancer
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https://www.omicsdi.org/dataset/ega/EGAS00001003659
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资源简介：
Brain metastasis (BM) of colorectal cancer (CRC) is rare but lethal, and lacks effective therapies or a good understanding of its genomic landscapes. We conduct an analysis of whole-exome sequencing (WES) and whole-genome sequencing (WGS) data on 19 trios of patient-matched BMs, primary CRC tumors, and adjacent normal tissue to (1) document genomic signatures during the evolution of CRC BM; (2) identify clinically actionable targets for the BM treatment; and (3) identify potential drivers in CRC BM.EGA study EGAS00001003659
创建时间：
2019-10-01
