Selective Activation of Enantiotopic C(sp3)−Hydrogen by Means of Chiral Phosphoric Acid: Asymmetric Synthesis of Tetrahydroquinoline Derivatives
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Chiral phosphoric acid-catalyzed asymmetric C−H functionalization has been achieved. In this process, enantiotopic C(sp3)−hydrogen is selectively activated by chiral phosphoric acid to afford tetrahydroquinoline derivatives with excellent enantioselectivities (up to 97% ee).
创建时间：
2016-02-23
