Construction of Multifunctional 3‑Amino-2-carbamimidoylacrylamides and Their Crystalline Channel-Type Inclusion Complexes

3-Amino-2-carbamimidoylacrylamides
were efficiently prepared via
a copper­(I)-catalyzed three-component reaction of sulfonylazides,
propriolamides, and amidines. The synthesized compounds provided three
kinds of crystalline structures based on the position of halogen.
Two of them presented channel-type inclusion complexes with ethyl
acetate through intermolecular hydrogen bonding, intermolecular C–H···π
and π–π interactions, and van der Waals forces.