Thrombin in complex with (S)-1-((R)-2-amino-3-cyclohexylpropanoyl)-N-(2-(aminomethyl)-5-chlorobenzyl) pyrrolidine-2-carboxamide
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/5lpd
下载链接
链接失效反馈官方服务：
资源简介：
Thrombin in complex with (S)-1-((R)-2-amino-3-cyclohexylpropanoyl)-N-(2-(aminomethyl)-5-chlorobenzyl) pyrrolidine-2-carboxamide Descriptor: (2~{S})-~{N}-[[2-(aminomethyl)-5-chloranyl-phenyl]methyl]-1-[(2~{R})-2-azanyl-3-cyclohexyl-propanoyl]pyrrolidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... Authors: Sandner, A, Heine, A, Klebe, G. Deposit date: 2016-08-12 Release date: 2017-07-26 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Strategies for Late-Stage Optimization: Profiling Thermodynamics by Preorganization and Salt Bridge Shielding. J.Med.Chem., 62, 2019
创建时间：
2016-08-12
