Demographic and neuropsychological data.

Values are represented as the mean ± SD. #p value for gender distribution in the three groups was obtained via a χ2 test. Separate ANOVA analysis was performed to investigate the group effect of age and neuropsychological data. NC: healthy controls, aMCI: amnestic mild cognitive impairment, AD: Alzheimer’s disease, MMSE: Mini-Mental Screening Examination, CDR: Clinical Dementia Rating, ADL: Activities of Daily Living, ACER: Addenbrooke’s Cognitive Examination Revised.*Post hoc test showed significant group difference between NC v.s. aMCI;†Post hoc test showed significant group difference between NC v.s. AD;‡Post hoc test showed significant group difference between aMCI v.s. AD. Post hoc pairwise comparison was performed through Fisher’s least significant difference (LSD) and pBold data indicated statistical significance.