Cdkl5

ENCODES a protein that exhibits small GTPase binding; ATP binding (ortholog); kinase activity (ortholog); INVOLVED IN neuron migration; positive regulation of axon extension; positive regulation of dendrite morphogenesis; ASSOCIATED WITH Angelman syndrome (ortholog); autistic disorder (ortholog); Christianson syndrome (ortholog); FOUND IN dendrite cytoplasm; dendritic growth cone; glutamatergic synapse; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil

编码一种表现出小GTPase结合、ATP结合（同源）、激酶活性（同源）特性的蛋白质；参与神经元迁移；正向调控轴突延伸；正向调控树突形态发生；与Angelman综合征（同源）相关；自闭症（同源）；Christianson综合征（同源）相关；存在于树突细胞质、树突生长锥、谷氨酸能突触中；与2,3,7,8-四氯二苯并-对-二恶英、3-氯丙烷-1,2-二醇、6-丙基-2-硫基尿嘧啶相互作用。