Endosomal Sequestration of Imidazoquinoline TLR7/8 Agonists Promotes Organ Partitioning and Dictates Kinetics of IFNα Release

Name: Endosomal Sequestration of Imidazoquinoline TLR7/8 Agonists Promotes Organ Partitioning and Dictates Kinetics of IFNα Release
Creator: Zenodo
Published: 2026-09-24T11:27:43+08:00

Zenodo2026-09-24 更新2026-10-01 收录

数据链接：

https://zenodo.org/doi/10.5281/zenodo.14233998 数据链接链接失效反馈

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资源简介：

1320- HsTLR7_1a 2024.3, 10A3 orthorombic, T3P, OPLS4, (all ionized compounds with pH 5.5 for dimeric protein)1321- HsTLR7_2a (TLR7 modelled from 6LW0) 160 ns/day (queue of 3 days)1322- HsTLR7_4r_a1323- HsTLR7_4s_a1324- HsTLR7_BNT411a1325- HsTLR7_IMDQ1326- HsTLR7_R8481327- HsTLR8_1a (TLR8 modelled from crystal 3W3L/5AWD)1328- HsTLR8_2a1329- HsTLR8_4r_a1330- HsTLR8_4s_a1331- HsTLR8_BNT411a1332- HsTLR8_IMDQ1333- HsTLR8_R848

提供机构：

Zenodo

创建时间：

2026-09-24