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Bypass of colibactin-induced DNA damage is mutagenic

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NIAID Data Ecosystem2026-05-10 收录
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The goal is to identify the mutational spectra resulting from bypass of a colibactin lesion in a model plasmid replicated in Xenopus egg extracts. Replication products were purified from extracts, and amplicons were generated by PCR and submitted to Azenta for paired-end next-generation sequencing (Illumina MiSeq, 2x250 bp).

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2025-09-15
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