Programmable base editing of RNA enables rewriting the genetic codes on specific sites. Current tools for specific RNA editing dependent on the assembly or recruitment of the guide RNA into an RNA/pro

NIAID Data Ecosystem40

ABE base editing raw sequence reads

碱基编辑

基因编辑效果评估

The NGS of adeninebase editor.

NIAID Data Ecosystem30

Increase base editing efficiency and product variety through fusion of Cas9 nickase to cytosine and adenosine deaminases

碱基编辑

CRISPR-Cas9

Base editors, which are created through fusion of Cas9 nickase to either cytidine or adenine deaminase, efficiently catalyze site-specific nucleotide conversions with minimal indel rates1, 2. However,

NIAID Data Ecosystem50

Programmable RNA base editing with a single engineered protein. Programmable RNA base editing with a single engineered protein

碱基编辑

基因治疗

NIAID Data Ecosystem30