Supplementary Tables.

Table A. GWAS quality control metrics. Table B: Genetic intercorrelations between the four retinal vasculature parameters. Table C. Most significant associations observed for the traits of interest. Table D. Replication of GWAS results in the EPIC-Norfolk cohort. Table E. Results of the meta-analyses of the UK Biobank and EPIC-Norfolk cohorts. Table F. Known loci replicated in trans-ancestry analysis combining Asian, African and European analysis. Table G. eQTL effects of SNPs associated in the GWAS. Table H. Functional analyses of causation for SNPs associated with AT. Table I: Ldsc genetic correlation between retinal parameters and systemic traits and disease. Table J. Mendelian randomisation analyses testing causality of vascular changes over metabolic traits. Table K. Mendelian randomisation analyses testing causality of metabolic traits over vascular changes. Table L. Replication of GWAS results in a recent publication (Zekavat BS et al., 2021). Table M. Comparison of part associations observed for the traits of interest with additional covariates (age2, smoking, diabetes). (XLSX)