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Warburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis

Name: Warburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis
Creator: The Second Hospital, Dalian Medical University
Published: 2023-07-10T13:48:57+08:00

integrated proteome resources2026-02-07 收录

肿瘤代谢重编程

化疗耐药机制

数据链接：

https://www.iprox.cn/page/project.html?id=IPX0006710000 数据链接链接失效反馈

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资源简介：

Warburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis

应用场景：

提供机构：

The Second Hospital, Dalian Medical University

创建时间：

2023-07-10

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化疗耐药机制

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ZEB1 inhibition sensitizes cells to the ATR inhibitor VE-821 by abrogating epithelial–mesenchymal transition and enhancing DNA damage

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The ataxia-telangiectasia-mutated (ATM) and rad3-related (ATR) checkpoint pathway plays an essential role in modulating cellular responses to replication stress and DNA damage to maintain genomic stab

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MRTF/SRF link the cytoskeleton and hedgehog pathway in drug-resistant basal cell carcinomas

化疗耐药机制

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We use multi-dimensional genomic analysis using mouse resistant BCCs to identify a non-canonical hedgehog activation pathway driven by the transcription factor, serum response factor (SRF). RNA and wh

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Warburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis

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