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RyR1 disease mutant Y523S with FKBP12.6, nanodisc and inhibitor dantrolene in the absence of calcium with refined P1 domain

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Protein Data Bank Japan2025-02-19 更新2026-06-30 收录
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https://pdbj.org/mine/summary/9cgp
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RyR1 disease mutant Y523S with FKBP12.6, nanodisc and inhibitor dantrolene in the absence of calcium with refined P1 domain Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Dantrolene, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... Authors: Iyer, K.A, Samso, M. Deposit date: 2024-06-30 Release date: 2024-12-11 Last modified: 2025-02-19 Method: ELECTRON MICROSCOPY (3.34 Å) Cite: Dantrolene inhibition of ryanodine receptor 1 carrying the severe malignant hyperthermia mutation Y522S visualized by cryo-EM. Structure, 33, 2025
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2024-06-30
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