RNA interference targets aberrant transcripts with cognate small interfering RNAs, which are derived from double-stranded RNA precursors. Several functional screens have identified Drosophila Blanks a
The RNA-induced silencing complex, comprising Argonaute and guide RNA, mediates RNA interference. Here we report the 3.2 Å crystal structure of Kluyveromyces Argonaute (KpAGO) fortuitously complexed w
Structural insights into small RNA sorting and mRNA binding by Arabidopsis Ago domains Descriptor: Protein argonaute 1, SULFATE ION Authors: Yuan, Y.A, Zha, X. Deposit date: 2012-01-11 Release date: 2
Argonaute proteins lie at the heart of the RNA-Induced Silencing Complex (RISC), wherein they use small RNA guides to recognize targets. Some Argonaute proteins can directly cleave their targets, wher
P granules are germ-cell-specific cytoplasmic structures containing RNA and protein and required for proper germ cell development in C. elegans. A new P-granule-associated protein, DEPS-1, whose loss
