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The role of fibronectin in the post natal lens

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NIAID Data Ecosystem2026-04-25 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP161613
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This trancriptome analysis reports genes that are differentially expressed upon deletion of the fibronectin gene from the lens during late embryonic development. Overall design: Lenses were isolated from two month Wild Type (WT) and Fibronectin Conditional Knockout mice (FNcKO) by microdissection (2 lenses/sample, three biological replicates/genotype) and total RNA was isolated. cDNA libraries were constructed using SMARTer Stranded Total RNA-Seq - Pico Input Mammalian, and sequenced using an Illumina NextSeq 500 (DNA Link USA, Inc) in an attempt to undestand the role of fibronectin in the post natal lens.
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2020-07-10
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